High temperature bromination Part XXIII: Bromination of octahydro-1H-indene and octahydro-1H-4,7-methanoindene

2-(4-Methoxy­phen­yl)-1H-indene

Excluding four H atoms, the molecule of the title compound, C(16)H(14)O, is almost planar, with an r.m.s. deviation of 0.0801 (2) Å. Due to p-π conjugation, the lengths of the two single bonds attached to the O atom are significantly different.

Bromination of Alkenes

The two most common halogenation reactions are chlorination and bromination. The addition of these halogens to alkenes yields 1,2-dihalides. Chlorinations reactions are used to synthesize over 6 million tons per year of ethylene dichloride (1,2-dichloroethane) for use as a solvent and for subsequent polymerization to produce poly(vinylchloride) known more commonly as PVC which is used for plumb...

Synthesis of enamines and their bromination

Selective Mono Bromination of 1,4-Dihydropyridines

2-monobromomethyl 1,4-dihydropyridines is selectively synthesized by bromination of the parent compound by 1.1 equivalents of pyridinium bromide perbromide in dichloromethane/pyridine at -20 °C. The same reagent in dichloromethane at 0 °C produce the 2,6-bis(bromomethyl) 1,4-dihydropyridines.

Unexpected bromination ring-opening of tetraarylporphyrins.

An unexpected, mild, efficient bromination ring-opening method has been developed for convenient synthesis of various novel biladienes or brominated porphyrins by controlling the amounts of NBS used.